من صفحة/ عالم التخدير
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#ادوية_التخدير
في الحالات الطارئة نحتاج #مرخي_عضلي سريع التأثير وبأقل اضرار على المريض 🎗 لذلك نستعمل دواء #سكولين Scoline ولكن #حديثا تم صناعة مرخي عضلي من نوع NDMRs سريع التأثير اسمه #Gantacurium فتابعوا ....
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#المقدمة
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👨🏫 يوجد لدينا دوائين نستعملها في الطوارىء لسرعتهما وهما :
🔹️ دواء #سكولين ولقد تحدثنا عنه سابقاً ...
🔹️ دواء Rocuronium او يسمى #ازميرون بجرعة 0.6-1.2 ملغم/كغم 🤔 ولكن هذه تعتبر جرعة عالية خاصة بعد الافاقة والخوف من رجوع تأثير المرخي كمضاعفات للدواء ....
لذلك جاءت #الفكرة بصناعة دواء له سرعة #السكولين و له صفات #الازميرون وهو دواء Gantacurium ...
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🥥 ينتمي دواء ال Gantacurium الى المرخيات العضلية نوع nondepolarizing neuromuscular blockers وله اسم ثاني هو #chlorofumarates .....
طيب 🧚♂️ ماهو مميزات هذا الدواء ؟؟؟
🥑 يبدا عمله بسرعة عالية Ultra-Short acting يعني خلال اقل من 60 ثانية وبعض المصادر تقول خلال 45 ثانية .
🥑 ينتهي عمله بعد 5-10 دقائق .
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#الجرعة_والتآثيرات
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🍉 يعطى بجرعة مقدارها 0.2 ملغم/كغم لعمل الانبوب الرغامي intubation dose .
🍉 التأثيرات الجانية :
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المصادر تقول بأنه امن لمرضى القلب والربو كونه لا يسبب تأثيرات جانية لكن هناك بحث نشر حديثا كالأتي :
● تم اعطاء ال Gantacurium لأربعة متطوعين بجرعة 0.5 ملغم/كغم فلاحظوا بأن شخص واحد فقط حدث له هبوط طفيف بضغط الدم مع زيادة طفيفة بدقات القلب ....
● تم اعطاء ال Gantacurium بجرعة 0.7 ملغم/كغم فلاحظوا اصابة ثلاث اشخاص بهبوط الضغط وارتفاع دقات القلب قليلا مع احمرار بسيط ....
#الاستنتاج
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🌽 يسبب هبوط ضغط الدم .
🌽 يسبب زيادة بسيطة بدقات القلب
🌽 احمرار بسيط cutaneous flushing
#ملاحظة
تظهر التأثيرات اعلاه فقط بجرعات عالية وللعلم تزول بعد مدة اقل من 2 دقيقة لذلك لا تحتاج اي تدخل علاجي .
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- المصدر :
صفحة عالم التخدير - امجد عدنان .
- رابط قناة عالم التخدير على التلغرام :
t.me/anaesthesia1994
From the page / The World of Anesthesia
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# Anesthetics
In case of emergency, we need a quick-impact muscle relaxant and minimal damage to the patient. Therefore, we use Scoline, but # newly developed a fast-acting NDMRs muscle strain called #Gantacurium.
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#Introduction
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👨🏫 We have two drugs we use in the emergency of their speed:
🔹️ # Sculin medicine We have talked about before ...
R Rocuronium is called اZimonon with a dose of 0.6-1.2 mg / kg 🤔 but this is considered a high dose, especially after recovery and fear of the return of the effect of the relaxant as complications of the drug.
So # the idea came with the manufacture of a drug with a speed of # sugars and has the characteristics of # Azimiron, a medicine Gantacurium ...
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🥥 Gantacurium belongs to the nondepolarizing neuromuscular blockers and its second name is #chlorofumarates .....
Ok 🧚️️ What are the advantages of this drug ???
🥑 It starts at ultra-short operating time in less than 60 seconds and some sources say within 45 seconds.
🥑 ends up after 5-10 minutes.
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#Dose and Effects
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🍉 A dose of 0.2 mg / kg is given to the intubation dose.
🍉 Adverse effects:
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Sources say it is safe for heart patients and asthma because it does not cause harmful effects, but there is research published recently as follows:
Gantacurium was given to four volunteers with a dose of 0.5 mg / kg. They observed that only one person had a slight drop in blood pressure with a slight increase in heart rate.
Gantacurium was given at a dose of 0.7 mg / kg. They noticed three people with decreased pressure and a slightly higher heart rate with a slight redness.
# Conclusion
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🌽 causes hypotension.
🌽 causes a slight increase in heart rate
C Cutaneous flushing
#Note
The above effects appear only at high doses and the flag disappears after less than 2 minutes so no therapeutic intervention is required.
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- Source :
Anesthesia World - Amjad Adnan.
- Link to the world of anesthesia on the Tigram:
t.me/anaesthesia1994
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